Grant Recipient – M2D2

The UMass M2D2 $100K Challenge announced award recipients at Mintz Levin, Boston on April 6th.  Cre8MDI was honored to be recognized along with other emerging-technology companies, such as Innoblative Designs, Astraeus Technologies, Fluid-Screen, LaunchPad Medical, and Biorasis.  In all, 72 companies competed for the recognition that goes along with the opportunity to present their technologies to potential investors and others in the medical device community.

Cre8MDI was awarded Honorable Mention and a cash prize for our presentation.  We thank all the sponsors who made these grants possible and for their continued commitment to advancing health technologies.  We also thank the M2D2 program staff for their efforts to execute a successful program with all the logistics behind such an event.  Cre8MDI looks forward to the potential for future collaboration with M2D2, the UMass Lowell engineering departments, and UMass Worcester medical staff and researchers.

m2d2 awards 2016


m2d2 winners

M2D2 Award Winners – Roy Wallen of Cre8MDI on far left.

UMASS M2D2 Press Release:


3D Printing

Our current prototype has been rendered with our Lulzbot 3D Printer. The current 3D representation showcases our proposed design for the final device.

3D Printing has been an outstanding tool for our team. We have been able to print samples of all our concepts. We use 3D printing to speed our development time by “instantly” being able to print mechanical parts including brackets, enclosures and new versions of our “egg.”

Pulse Wave Velocity (PWV)

Microsoft Word - PWV.docx


Cre8MDI’s approach to assessing arterial stiffness is based on the gold standard method of measuring aortic (carotid to femoral) pulse wave velocity (PWV). PWV is a well-established index of arterial stiffness and its first clinical use can be traced to Bramwell and the Nobel laureate, A.V. Hill in 1922.

A pulse wave travels from the heart down the arterial wall in advance of blood flow during each heartbeat. The velocity of a pulse wave which propagates in an artery is dependent on the stiffness of that portion of the artery. The more rigid the wall of the artery, the faster the wave moves.

The European Society of Hypertension officially recommended PWV to be part of all routine exams for high blood pressure patients since 2007.

PWV has predictive value on future cardiovascular events such as strokes or heart attaches. This means that people actively monitoring their PWV, will have a longer time horizon to take proactive measures which may stop or reverse these devastating disease. Early diagnosis is the key to better health.



How many of you have been affected by heart attack, stroke, or other cardiovascular complications? Do you know someone who has had a heart attack, stroke, or worse – lost their life because of an undetected heart condition?

At Cre8MDI we have been affected by heart disease, both personally and through family members’ experiences. Heart disease is the leading cause of death in America and the fourth leading cause is another cardiovascular disease, Stroke. Both are preventable through changes in diet and lifestyle and or medications, but most people do not even know when they are at risk. Knowing is half the battle.

Our device, once completed will determine the stiffness of your arteries, thereby telling you your risk before you have any symptoms. It measures the condition of your arteries with sensor technology by using Pulse Wave Velocity (PWV). A stiff artery means that the heart must work overtime to maintain the circulation of nutrients and blood flow to the rest of the body. When blood doesn’t reach the brain, a stroke occurs. When the heart is over-worked; it results in a heart attack.

Currently patients rely on blood pressure to tell them if they may have a cardiovascular disease, however this is not the most accurate way to determine your risk.  You must account for hereditary factors, lifestyle choices (what you eat, how much you exercise), environmental components, and stress.  Blood pressure can go up or down, but never tells us the condition of your arteries.  Once a symptom occurs or risk factor is identified patients then undergo costly tests like MRIs and EKGs. These tests can be avoided or minimized if the condition of patients’ arteries begin being monitored sooner and more simply – like at their primary care physician’s office.

Our hope is to one day have our device in every Primary Care Physican’s office so patients can be best informed of their risk for CVD. Then they can make the necessary dietary and lifestyle changes before it’s too late.

cre8 device promo

Predicting Cardiovascular Disease with Ease!

Cre8MDI is a medical device startup company which designs, develops, and patents medical devices. Our mission is to develop and commercialize innovative diagnostic devices that will improve the quality of healthcare and reduce cost through prediction, early detection, and monitoring.

In early 2014 we launched a successful crowdfunding campaign to fund our next stage prototype. Please take a few moments to view our video and find out more about Cre8MDI and how we are “Predicting Cardiovascular Disease with Ease!”